STUDY FINDS PSILOCYBIN ASSOCIATED WITH SIGNIFICANT DECREASE IN DEPRESSION

CCJ Gabriel
STUDY FINDS PSILOCYBIN ASSOCIATED WITH SIGNIFICANT DECREASE IN DEPRESSION

A new study has found that psilocybin use is associated with significant and persistent reductions in depression, anxiety, alcohol misuse, emotional regulation, spiritual well being, and extraversion. Researchers at Johns Hopkins University, Ohio State University, and Unlimited Sciences conducted the largest prospective survey of naturalistic psilocybin use to date, revealing evidence supporting the potential for psilocybin to produce lasting improvements in mental health symptoms and general wellbeing. The study, published in the journal Frontiers in Psychiatry, recruited 2,833 adults and administered multiple surveys before and after using the psychedelic outside of the clinical setting. The results showed persisting reductions in anxiety, depression, and alcohol misuse, increased cognitive flexibility, emotion regulation, spiritual well being, and extraversion, and reduced neuroticism and burnout after psilocybin use. The most common reason for taking psilocybin was for self-exploration (81%), followed by mental health (71%), therapy (48%), creativity (44%), recreation (38%), productivity (22%), and physical health (14%). About 3 in 4 respondents set an intention before using the psychedelic. The average dose of psilocybin was 3.1 grams. The study also found that 22% of respondents met the criteria for having a "complete mystical experience," a significant predictor of changes in multiple longitudinal variables including decreased depression, personal burnout, work burnout, and state anxiety. Overall, the study found persistent reductions in depression, anxiety, and alcohol misuse after psilocybin use, consistent with clinical studies. This research is part of a growing body of research on psychedelics, as lawmakers and advocates work to enact reform. The National Institute on Drug Abuse is seeking proposals for research initiatives to explore psychedelic use for drug addiction treatment.

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