Caryophyllene: The spicy terpene.
It has a much larger molecule than other terpenes, such as myrcene and limonene. Its molecular structure has something called a cyclobutane ring. It’s not found in any terpene, making it pretty rare. Its aroma and diverse flavour profile make it instantly recognizable. Alongside cannabis, you might also recognize it as being present in spices like pepper, basil, oregano, and cinnamon. Its aroma and diverse flavour profile make it instantly recognizable. Cannabis strains with high amounts of caryophyllene are either spicy or musky. It’s almost like taking a quick whiff of pepper. There are notes of diesel and fuel that almost cause the nose to tingle. Many unique aspects make caryophyllene stand out in the crowd. Let’s get into it!
Function
Cannabis products containing caryophyllene affect the body in multiple ways. Here’s what research finds. Products containing caryophyllene are shown to enhance wound healing. Studies suggest this terpene decreases inflammation, which reduces various types of pain. Improved cell migration allows wounds to heal quicker than those that haven’t been treated. THC hits hard and can cause an overwhelming sensation when it’s ingested. There is a possibility that caryophyllene decreases its harsh effects on the body. However, more research is required to confirm this point because the terpene does not interact with the CB1 receptor.
Entourage Effect
How does caryophyllene interact with other cannabinoids? It’s time to find out! Scientific research shows that this terpene mainly interacts with CB2 receptors. Caryophyllene binds to CB2 receptors that are found within our peripheral endocannabinoid system. As a result, it does not cause the euphoric feeling of getting high, but still boasts anti-inflammatory properties. Caryophyllene is found in over 500 compounds. Out of those, only four interact with CB2 receptors. Alongside caryophyllene, delta9-THC, delta8-THC, and CBN can interact with them.